O-α-D-Glucopyranosyl Emtricitabine

Ref. TR-E254500

Product Information

• Name: O-α-D-Glucopyranosyl Emtricitabine
• Synonyms: 5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-4-[[3,5,6-trihydroxy-2-oxo-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexyl]amino]pyrimidin-2-one

Description

Applications Emtricitabine Amadori Rearrangement Product is an impurity of Emtricitabine(E525000) which is a reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).
References FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: . Dis., 182, 599 (2000)

• Brand: TRC

Chemical properties

• Molecular weight: 571.528
• Formula: C₂₀H₃₀FN₃O₁₃S
• Color/Form: Neat
• InChI: InChI=1S/C20H30FN3O13S/c21-7-2-24(11-6-38-12(5-27)36-11)20(34)23-18(7)22-1-8(28)13(30)17(9(29)3-25)37-19-16(33)15(32)14(31)10(4-26)35-19/h2,9-17,19,25-27,29-33H,1,3-6H2,(H,22,23,34)
• InChI key: InChIKey=PYYCXOWAAZJZFT-UHFFFAOYSA-N
• SMILES: O=C(CNc1nc(=O)n(C2CSC(CO)O2)cc1F)C(O)C(OC1OC(CO)C(O)C(O)C1O)C(O)CO