Eflornithine Hydrochloride Monohydrate

CAS: 96020-91-6

Ref. TR-E436000

Product Information

• Name: Eflornithine Hydrochloride Monohydrate
• Synonyms: Ornithine, 2-(difluoromethyl)-, hydrochloride, hydrate (1:1:1), DL-Ornithine, 2-(difluoromethyl)-, monohydrochloride, monohydrate, Ornithine, 2-(difluoromethyl)-, monohydrochloride, monohydrate (9CI), 2,5-Diamino-2-(Difluoromethyl)Pentanoic Acid, 2,5-Diamino-2-(difluoromethyl)pentanoic acid hydrate hydrochloride, <span class="text-smallcaps">DL</span>-Ornithine, 2-(difluoromethyl)-, monohydrochloride, monohydrate, DFMO Eflornithine, DMFO HCl, Eflornithine hydrochloride monohydrate, H-alpha-Difluoro-Me-DL-Orn-OH.HCl.H2O, Ornithine, 2-(difluoromethyl)-, hydrochloride, hydrate (1:1:1), Ornithine, 2-(difluoromethyl)-, monohydrochloride, monohydrate
• CAS: 96020-91-6

Description

Applications Irreversible inhibitor of ornithine decarboxylase, an enzyme involved in polyamine biosynthesis. Antineoplastic; antipneumocystic; antiprotozoal (Trypanosoma). Used in the treatment of hirsutism.
References Bacchi, C.J., et al.: Science, 210, 332 (1980); Haegele, K.D., et al.: Clin. Pharmacol. Ther., 30, 210 (1981); Meyskens, F.L., et al.: Clin. Cancer Res., 5, 945 (1999);

• Brand: TRC

Chemical properties

• Molecular weight: 236.64
• Formula: C₆H₁₂F₂N₂O₂•HCl•HO
• Color/Form: Neat
• InChI: 1H, 1H2, InChI=1S/C6H12F2N2O2.ClH.H2O/c7-4(8)6(10,5(11)12)2-1-3-9, , /h4H,1-3,9-10H2,(H,11,12)
• InChI key: InChIKey=FJPAMFNRCFEGSD-UHFFFAOYSA-N
• SMILES: Cl.NCCCC(N)(C(=O)O)C(F)F.O