Product Information
Name:Eltrombopag-d3
Controlled Product
Synonyms:
- 3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid-d3
- SB 497115-d3
Brand:TRC
Description:
Applications Eltrombopag-d3 is an isotopic analog of Eltrombopag (E508000) which is an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.
References Bussel, J., et al.: New Eng. J. Med., 357, 2237 (2007), Marsilje, T., et al.: Bioorg. Med. Chem. Lett., 18, 5259 (2008), Alper, P., et al.: Bioorg. Med. Chem. Lett., 18, 5255 (2008),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:445.485
Formula:C25D3H19N4O4
Color/Form:Neat
InChI:InChI=1S/C25H22N4O4/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33/h4-13,26,30H,1-3H3,(H,32,33)/b27-22-/i5D,8D,9D
InChI key:InChIKey=XDXWLKQMMKQXPV-FDGHPJOQSA-N
SMILES:[2H]c1c([2H])c(N/N=C2\C(=O)N(c3ccc(C)c(C)c3)N=C2C)c(O)c(-c2cccc(C(=O)O)c2)c1[2H]
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