- Quinazoline and Quinoline Derivatives
- Salts and Derivatives of Active Pharmaceutical Ingredients (API)
Product Information
Name:Eltrombopag Methyl Ester
Synonyms:
- 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxylic Acid Methyl Ester
Brand:TRC
Description:Applications Eltrombopag Methyl Ester, is a metabolite of Eltrombopag (E508000), which is an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.References Bussel, J., et al.: New Eng. J. Med., 357, 2237 (2007), Marsilje, T., et al.: Bioorg. Med. Chem. Lett., 18, 5259 (2008), Alper, P., et al.: Bioorg. Med. Chem. Lett., 18, 5255 (2008),
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Chemical properties
Molecular weight:456.49
Formula:C26H24N4O4
Color/Form:Neat
InChI:InChI=1S/C26H24N4O4/c1-15-11-12-20(13-16(15)2)30-25(32)23(17(3)29-30)28-27-22-10-6-9-21(24(22)31)18-7-5-8-19(14-18)26(33)34-4/h5-14,29,31H,1-4H3
InChI key:InChIKey=GFBMVYONHLIMFU-NFFVHWSESA-N
SMILES:COC(=O)c1cccc(-c2cccc(N/N=C3\C(=O)N(c4ccc(C)c(C)c4)N=C3C)c2O)c1
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