Emtricitabine

CAS: 143491-57-0

Ref. TR-E525000

Product Information

• Name: Emtricitabine
• Synonyms: 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2R-cis)-, 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv., 4-Amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone, (-)-2',3'-Dideoxy-5-fluoro-3'-thiacytidine, (-)-2'-Deoxy-5-fluoro-3'-thiacytidine, (-)-FTC, 524W91, BW 1592, BW 524W91, Coviracil, Emtriva, (-)-FTC, (-)-2′,3′-Dideoxy-5-fluoro-3′-thiacytidine, (-)-Beta-2',3'-Dideoxy-5-Fluoro-3'-Thiacytidine, (-)-Ftc, 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv., 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-5-oxathiolanyl]-, 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2R-cis)-, 4-Amino-5-Fluoro-1-(2-(Hydroxymethyl)-1,3-Oxathiolan-5-Yl)-(2R-Cis)-2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one, Bw 1592, Bw 524W91, Emitricibatine, Emitricitabine, Emtricitabin, Emtritabine, Fumitremorgin C, Sm-Q

Description

Applications A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).
References FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: . Dis., 182, 599 (2000)

• Brand: TRC

Chemical properties

• Molecular weight: 247.25
• Formula: C₈H₁₀FN₃O₃S
• Color/Form: Light Yellow
• InChI: InChI=1S/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1,5-6,13H,2-3H2,(H2,10,11,14)/t5-,6+/m0/s1
• InChI key: InChIKey=XQSPYNMVSIKCOC-NTSWFWBYSA-N
• SMILES: Nc1nc(=O)n([C@@H]2CS[C@H](CO)O2)cc1F