CAS 143491-57-0
:emtricitabine
Description:
Emtricitabine is an antiretroviral medication primarily used in the treatment of HIV infection. It belongs to the class of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs). The chemical formula for emtricitabine is C₁₃H₁₅N₃O₃S, and it features a thiophene ring, which contributes to its unique properties. Emtricitabine is characterized by its ability to inhibit the reverse transcriptase enzyme, thereby preventing the replication of the virus. It is typically administered orally and is well-absorbed in the gastrointestinal tract. The drug is known for its favorable pharmacokinetic profile, including a long half-life, which allows for once-daily dosing. Emtricitabine is often used in combination with other antiretroviral agents to enhance efficacy and reduce the risk of resistance. Common side effects may include gastrointestinal disturbances and skin rashes, but it is generally well-tolerated. Its effectiveness and safety profile have made it a key component in HIV treatment regimens worldwide.
Formula:C8H10FN3O3S
InChI:InChI=1/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1,5-6,13H,2-3H2,(H2,10,11,14)
InChI key:InChIKey=XQSPYNMVSIKCOC-NTSWFWBYSA-N
SMILES:O=C1N([C@H]2O[C@@H](CO)SC2)C=C(F)C(N)=N1
Synonyms:- (-)-2',3'-Dideoxy-5-fluoro-3'-thiacytidine
- (-)-2'-Deoxy-5-fluoro-3'-thiacytidine
- (-)-2′,3′-Dideoxy-5-fluoro-3′-thiacytidine
- (-)-Beta-2',3'-Dideoxy-5-Fluoro-3'-Thiacytidine
- (-)-Ftc
- 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv.
- 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-
- 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-5-oxathiolanyl]-
- 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2R-cis)-
- 4-Amino-5-Fluoro-1-(2-(Hydroxymethyl)-1,3-Oxathiolan-5-Yl)-(2R-Cis)-2(1H)-Pyrimidinone
- 4-Amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
- 4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
- 524W91
- Bw 1592
- Bw 524W91
- Coviracil
- Emitricibatine
- Emitricitabine
- Emtricitabin
- Emtritabine
- Emtriva
- Fumitremorgin C
- Sm-Q
- EMTRICITABINE
- 4-Amino-5-fluoro-1-[(2R,5S)-2-hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H-pyrimidinone, (-)-FTC, (-)--2’,3’-Dideoxy-5-fluoro-3’-thiacytidine, 524W91, BW-52491, Coviracil
- 4-Amino-5-fluoro-1-[(2R,5S)-2-hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H-pyrimidinone, (-)-FTC, (-)-b-23Dideoxy-5-fluoro-3thiacytidine, 524W91, BW-52491, Coviracil,
- 4-Amino-5-fluoro-1-[(2R,5S)-2-hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H-pyrimidinone,(-)-FTC,(-)-b-23Dideoxy-5-flu
- Entricitabine
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Emtricitabine
CAS:Formula:C8H10FN3O3SPurity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:247.24Emtricitabine
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C8H10FN3O3SColor and Shape:White Off-White Crystalline PowderMolecular weight:247.04269Emtricitabine
CAS:EmtricitabineFormula:C8H10FN3O3SPurity:98%Color and Shape:SolidMolecular weight:247.25Emtricitabine
CAS:Formula:C8H10FN3O3SPurity:≥ 98.0%Color and Shape:White to off-white crystalline powderMolecular weight:247.25Emtricitabine
CAS:Controlled ProductFormula:C8H10FN3O3SColor and Shape:Light YellowMolecular weight:247.25Emtricitabine
CAS:Emtricitabine is a nucleoside reverse transcriptase inhibitor with anti-human immunodeficiency virus (HIV) and hepatitis B virus activity.Cost-effective and quality-assured.Formula:C8H10FN3O3SPurity:99.15% - 99.78%Color and Shape:White PowderMolecular weight:247.25Emtricitabine
CAS:Applications A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).
References FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: . Dis., 182, 599 (2000)Formula:C8H10FN3O3SColor and Shape:NeatMolecular weight:247.25Emtricitabine - Bio-X ™
CAS:Emtricitabine is an antiviral drug that is used to treat chronic viral hepatitis, which is caused by the hepatitis B and C viruses. The drug blocks the activity of reverse transcriptase, which is an enzyme necessary for the replication of viral RNA in the body. Emtricitabine has been shown to be effective against acute hepatitis B virus infection and chronic hepatitis B virus infection with or without cirrhosis. It also has been shown to be effective against chronic hepatitis C virus infection with or without cirrhosis.
Formula:C8H10FN3O3SPurity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:247.25 g/mol2',3'-Dideoxy-5-fluoro-3'-thiacytidine
CAS:Emtricitabine is a nucleoside analog that is an antiviral drug used to treat HIV/AIDS. It is a synthetic nucleoside analog of cytidine, in which the 3' phosphate and 5' hydroxyl groups have been replaced with a fluorine atom and a methoxy group, respectively. Emtricitabine has been shown to inhibit the synthesis of viral DNA by competing for incorporation into the viral DNA strand during the elongation phase of viral replication. Emtricitabine also has anticancer activity, but no other known therapeutic uses.Formula:C8H10FN3O3SPurity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:247.25 g/mol4-Amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
CAS:Formula:C8H10FN3O3SPurity:95%Color and Shape:SolidMolecular weight:247.24Emtricitabine System Suitability Mixture A (Emtricitabine; 5-epi Emtricitabine)
CAS:Controlled ProductFormula:MixtureVisitourWebsiteColor and Shape:MixtureMolecular weight:Mixture - Visit our WebsiteEmtricitabine-d2,15N
CAS:Controlled ProductFormula:C8D2H8F15NN2O3SColor and Shape:NeatMolecular weight:250.252Emtricitabine (1 mg/mL in Methanol)
CAS:Formula:C8H10FN3O3SColor and Shape:Single SolutionMolecular weight:247.25Emtricitabine Phosphonic Acid Triethylammonium Salt
CAS:Controlled ProductApplications (-)-Emtricitabine (E525000) derivative.
Formula:C8H10FN3O5PS·C6H13NColor and Shape:NeatMolecular weight:409.393
