Entinostat(MS-27-275)

CAS: 209783-80-2

Ref. TR-E559300

Product Information

• Name: Entinostat(MS-27-275)
• Synonyms: pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate, (Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate, Carbamic acid, N-[[4-[[(2-aminophenyl)amino]carbonyl]phenyl]methyl]-, 3-pyridinylmethyl ester, Carbamic acid, [[4-[[(2-aminophenyl)amino]carbonyl]phenyl]methyl]-, 3-pyridinylmethyl ester, Ms 27-275, Ms 275, Ms 275-27, N-[4-[N-(2-Aminophenyl)carbamoyl]benzyl]carbamic acid 3-pyridylmethyl ester, N-[[4-[[(2-Aminophenyl)amino]carbonyl]phenyl]methyl]carbamic acid 3-pyridinylmethyl ester, Pyridin-3-Ylmethyl {4-[(2-Aminophenyl)Carbamoyl]Benzyl}Carbamate, Sndx 275

Description

Applications Entinostat is an emerging HDACi (histone deacetylase inhibitor). Entinostat is used for treatment of solid tumors and hematologic malignancies. Potent Histone deacetylase inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hu, E., et al.: J. Pharmacol. Exp. Ther., 307, 720 (2003), Maggio, S., et al.: Cancer Res., 64, 2590 (2004), Gojo, I., et al.: Blood, 109, 2781 (2007), Xu, W; Oncogene, 26, 5541 (2007),

• Brand: TRC

Chemical properties

• Molecular weight: 376.41
• Formula: C₂₁H₂₀N₄O₃
• Color/Form: Neat
• InChI: InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26)
• InChI key: InChIKey=ASVIATVNEHCBMY-QYQXPSDSSA-N
• SMILES: CC.CCC.CN[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N(C)C(C=O)[C@H](OC(C)=O)[C@H](C)CC=O)C(C)C