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Epacadostat
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Epacadostat

CAS: 1204669-58-8

Ref. TR-E565503

5mg
94.00 €
50mg
577.00 €
100mg
886.00 €
Estimated delivery in United States, on Wednesday 15 Jan 2025

Product Information

Name:
Epacadostat
Controlled Product
Synonyms:
  • 1,2,5-Oxadiazole-3-carboximidamide
  • 4-[[2-[(aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-
  • [C(Z)]-
  • [C(Z)]-4-[[2-[(Aminosulfonyl)amino]ethyl]amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide
  • ICBN 24360
  • INCB 024360
Description:

Applications Epacadostat is a potent and novel indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM. It has high selectivity over IDO2 and tryptophan 2,3-dioxygenase (TDO).
References Yue, Eddy W., et al.: ACS Med. Chem. Lett., 8, 486 (2017);

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
438.23
Formula:
C11H13BrFN7O4S
Color/Form:
Neat
InChI:
InChI=1S/C11H13BrFN7O4S/c12-7-5-6(1-2-8(7)13)17-11(18-21)9-10(20-24-19-9)15-3-4-16-25(14,22)23/h1-2,5,16,21H,3-4H2,(H,15,20)(H,17,18)(H2,14,22,23)
InChI key:
InChIKey=NPTIPEQJIDTVKR-STQMWFEESA-N
SMILES:
c1cc2c3c(c1)[C@H]1CCC[C@H]1CN3CCNC2
MDL:
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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