(-)-Epigallocatechin Gallate

CAS: 989-51-5

Ref. TR-E588500

Product Information

• Name: (-)-Epigallocatechin Gallate
• Synonyms: Benzoic acid, 3,4,5-trihydroxy-, (2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester, Benzoic acid, 3,4,5-trihydroxy-, 3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester, (2R-cis)-, Epigallocatechol, 3-gallate (7CI), Epigallocatechol, 3-gallate, (-)- (8CI), Epigallocatechol, gallate (6CI), Gallic acid, 3-ester with epigallocatechol, (-)- (8CI), (-)-Epigallocatechin 3-O-gallate, (-)-Epigallocatechin 3-gallate, (-)-Epigallocatechol gallate, (-)-epi-Gallocatechin 3-O-gallate, 3-O-Galloyl-(-)-epigallocatechin, EGCG, Epigallocatechin 3-O-gallate, Epigallocatechin 3-gallate, Epigallocatechin-3-monogallate, L-Epigallocatechin gallate, NVP-XAA 723, PF-EGCg 90, Teavigo, Theliokeep, epi-Gallocatechin 3-O-gallate
• Brand: TRC

Description

Applications (-)-Epigallocatechin Gallate is a tumor-inhibiting constituent of green tea. (-)-Epigallocatechin Gallate alters the cleavage of amyloid precursor protein, decreasing production of amaloid-ß and amaloid plaques in mice. This compound has neuroprotective properties.
References Yamane, T. et al.: Cancer Res., 55, 2081 (1995); Tan, J. et al.: J. Neurosci. 25, 8807 (2005);

Chemical properties

• Molecular weight: 458.37
• Formula: C₂₂H₁₈O₁₁
• Color/Form: Neat
• InChI: InChI=1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21-/m1/s1
• InChI key: InChIKey=WMBWREPUVVBILR-WIYYLYMNSA-N
• SMILES: O=C(O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1