Epi Lovastatin

CAS: 79952-44-6

Ref. TR-E588530

Product Information

• Name: Epi Lovastatin
• Synonyms: (1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2R)-2-methylbutanoate, Butanoic acid, 2-methyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester, [1S-[1a(S*),3a,7b,8b(2S*,4S*),8ab]]- (9CI), Butanoic acid, 2-methyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester, [1S-[1a(S*),3a,7b,8b(2S*,4S*),8ab]]- (9CI), Simvastatin Impurity F, Epilovastatin, Butanoic acid, 2-methyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (2R)-, Butanoic acid, 2-methyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester, [1S-[1α(S*),3α,7β,8β(2S*,4S*),8aβ]]-

Description

Impurity Simvastatin EP Impurity F
Applications Epi Lovastatin (Simvastatin EP Impurity F) is a Lovastatin impurity; an antihypercholesterolemic compound.
References Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986),

• Brand: TRC

Chemical properties

• Molecular weight: 404.54
• Formula: C₂₄H₃₆O₅
• Color/Form: Neat
• InChI: InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15+,16-,18+,19+,20-,21-,23-/m0/s1
• InChI key: InChIKey=PCZOHLXUXFIOCF-YPQFMRJXSA-N
• SMILES: CC[C@@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@H]21