14,15-Epoxyeicosatrienoic Acid

CAS: 197508-62-6

Ref. TR-E589138

Product Information

• Name: 14,15-Epoxyeicosatrienoic Acid
• Synonyms: (5Z,8Z,11Z)-13-(3-pentyloxiran-2-yl)trideca-5,8,11-trienoic acid
• CAS: 197508-62-6

Description

Applications Epoxyeicosatrienoic Acid (EET) has antihypertensive and anti-inflammatory properties and play a role in the maintenance of renal vascular function. N,​N'-​dicyclohexylurea (DCU) increased release of 14,15-EET when the cells were stimulated with a calcium ionophore.Also, it is derived from Arachidonic Acid >97% (A765000), which is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and Arachidonic Acid is also a constituent of animal phosphatides.
References Zhao, X., et al.: J. Am. Soc. Nephrol., 15, 1244 (2004); Fang, X., et al.: J. Biol. Chem., 276, 14867 (2001); Kurosawa, T., et al.: J. Cell. Physiol., 219, 606 (2009); Mazalli, M., et al.: J. Agric. Food Chem., 57, 5028 (2009);

• Brand: TRC

Chemical properties

• Molecular weight: 320.466
• Formula: C₂₀H₃₂O₃
• Color/Form: Neat
• InChI: InChI=1S/C20H32O3/c1-2-3-12-15-18-19(23-18)16-13-10-8-6-4-5-7-9-11-14-17-20(21)22/h4,6-7,9-10,13,18-19H,2-3,5,8,11-12,14-17H2,1H3,(H,21,22)/b6-4-,9-7-,13-10-
• InChI key: InChIKey=JBSCUHKPLGKXKH-ILYOTBPNSA-N
• SMILES: CCCCCC1OC1C/C=C\C/C=C\C/C=C\CCCC(=O)O