Epristeride

CAS: 119169-78-7

Ref. TR-E590055

Product Information

• Name: Epristeride
• Synonyms: (17β)-17-[[(1,1-Dimethylethyl)amino]carbonyl]androsta-3,5-diene-3-carboxylic Acid, 17β-(tert-Butylcarbamoyl)androsta-3,5-diene-3-carboxylic Acid, N-tert-Butylandrosta-3,5-diene-17β-carboxamide-3-carboxylic Acid, ONO 9302, SKF 105657, (17b)-17-[[(1,1-Dimethylethyl)amino]carbonyl]androsta-3,5-diene-3-carboxylic Acid, (17beta)-17-(tert-Butylcarbamoyl)androsta-3,5-diene-3-carboxylic acid, 119169-78-7, 17-(Tert-Butylcarbamoyl)Androsta-3,5-Diene-3-Carboxylic Acid, 17β-(tert-Butylcarbamoyl)androsta-3,5-diene-3-carboxylic acid, Androsta-3,5-Diene-3-Carboxylic Acid, 17-[[(1,1-Dimethylethyl)Amino]Carbonyl]-, (17Beta)-, Androsta-3,5-diene-3-carboxylic acid, 17-[[(1,1-dimethylethyl)amino]carbonyl]-, (17β)-, N-tert-Butylandrosta-3,5-diene-17β-carboxamide-3-carboxylic acid, Ono 9302, Skf 105657

Description

Applications Epristeride is a selective and specific uncompetitive inhibitor of human steroid 5α-reductase isoform 2. It is used in the treatment of benign prostatic hyperplasia.
References Levy, M., et al.: J. Steroid Biochem. Mol. Biol., 48, 197 (1994); Smith, C., et al.: J. Clin. Endocrinol. Metab., 81, 1361 (1996);

• Brand: TRC

Chemical properties

• Molecular weight: 399.566
• Formula: C₂₅H₃₇NO₃
• Color/Form: Neat
• InChI: InChI=1S/C25H37NO3/c1-23(2,3)26-21(27)20-9-8-18-17-7-6-16-14-15(22(28)29)10-12-24(16,4)19(17)11-13-25(18,20)5/h6,14,17-20H,7-13H2,1-5H3,(H,26,27)(H,28,29)/t17-,18-,19-,20+,24-,25-/m0/s1
• InChI key: InChIKey=VAPSMQAHNAZRKC-PQWRYPMOSA-N
• SMILES: CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C=C(C(=O)O)CC[C@]4(C)[C@H]3CC[C@]12C