Product Information
Name:EPZ-015666
Controlled Product
Synonyms:
- N-[(2S)-3-(3,4-Dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-6-(3-oxetanylamino)-4-pyrimidinecarboxamide
Brand:TRC
Description:Applications EPZ015666 is a potent, orally bioavailable inhibitor of Protein arginine methyltransferase 5 (PRMT5). It acts by blocking the association of PRMT5 with methylosome protein 50.References Duncan, K., et al.: PCT Int. Appl. (2014), WO 2014100719 A2 20140626
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:383.44
Formula:C20H25N5O3
Color/Form:Neat
InChI:InChI=1S/C20H25N5O3/c26-17(10-25-6-5-14-3-1-2-4-15(14)9-25)8-21-20(27)18-7-19(23-13-22-18)24-16-11-28-12-16/h1-4,7,13,16-17,26H,5-6,8-12H2,(H,21,27)(H,22,23,24)/t17-/m0/s1
InChI key:InChIKey=ZKXZLIFRWWKZRY-UHFFFAOYSA-N
SMILES:O=C(NCC(O)CN1CCc2ccccc2C1)c1cc(NC2COC2)ncn1
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