Estimated delivery in United States, on Friday 23 Aug 2024
Product Information
Name:
EPZ-015666
Controlled Product
Synonyms:
- N-[(2S)-3-(3,4-Dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-6-(3-oxetanylamino)-4-pyrimidinecarboxamide
Description:
Applications EPZ015666 is a potent, orally bioavailable inhibitor of Protein arginine methyltransferase 5 (PRMT5). It acts by blocking the association of PRMT5 with methylosome protein 50.
References Duncan, K., et al.: PCT Int. Appl. (2014), WO 2014100719 A2 20140626
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
383.44
Formula:
C20H25N5O3
Color/Form:
Neat
InChI:
InChI=1S/C20H25N5O3/c26-17(10-25-6-5-14-3-1-2-4-15(14)9-25)8-21-20(27)18-7-19(23-13-22-18)24-16-11-28-12-16/h1-4,7,13,16-17,26H,5-6,8-12H2,(H,21,27)(H,22,23,24)/t17-/m0/s1
InChI key:
InChIKey=ZKXZLIFRWWKZRY-UHFFFAOYSA-N
SMILES:
O=C(NCC(O)CN1CCc2ccccc2C1)c1cc(NC2COC2)ncn1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-E592100 EPZ-015666
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