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Product Information
- N-[(2S)-3-(3,4-Dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-6-(3-oxetanylamino)-4-pyrimidinecarboxamide
Applications EPZ015666 is a potent, orally bioavailable inhibitor of Protein arginine methyltransferase 5 (PRMT5). It acts by blocking the association of PRMT5 with methylosome protein 50.
References Duncan, K., et al.: PCT Int. Appl. (2014), WO 2014100719 A2 20140626
Chemical properties
Technical inquiry about: TR-E592100 EPZ-015666
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