Eritadenine

CAS: 23918-98-1

Ref. TR-E600100

Product Information

• Name: Eritadenine
• Synonyms: (aR,ßR)-6-Amino-a,ß-dihydroxy-9H-purine-9-butanoic Acid, 4-(6-Amino-9H-purin-9-yl)-4-deoxy-D-erythronic Acid, 4-(6-Aminopurin-9-yl)-4-deoxy-D-erythronic Acid, Lentinacin, Lentysine, 4-(9-Adenyl)-D-erythro-2,3-dihydroxybutyric Acid, D-Eritadenine, (αR,βR)-6-Amino-α,β-dihydroxy-9H-purine-9-butanoic acid, 23918-98-1, 4-(6-Amino-9H-purin-9-yl)-4-deoxy-<span class="text-smallcaps">D</span>-erythronic acid, 4-(6-Aminopurin-9-yl)-4-deoxy-<span class="text-smallcaps">D</span>-erythronic acid, 4-(9-Adenyl)-<span class="text-smallcaps">D</span>-erythro-2,3-dihydroxybutyric acid, 9H-Purine-9-butanoic acid, 6-amino-α,β-dihydroxy-, (αR,βR)-, 9H-Purine-9-butanoic acid, 6-amino-α,β-dihydroxy-, [R-(R*,R*)]-, <span class="text-smallcaps">D</span>-Eritadenine, Erythronic acid, 4-(6-amino-9H-purin-9-yl)-4-deoxy-, <span class="text-smallcaps">D</span>-, [R-(R*,R*)]-6-Amino-a,b-dihydroxy-9H-purine-9-butanoic Acid

Description

Applications Hypocholesterolemic isolated from shiitake mushrooms, effecting phospholipid and linoleic acid metabolisms. Specifically, Eritadenine is a potent inhibitor of S-adenosyl-L-homocysteine hydrolase (SAHH), decreasing total cholesterol levels in plasma.
References Fukada, S., et al.: J. Nut., 136, 2797 (2006), Vilar, S., et al.: J. Med. Chem., 49, 1118 (2006), Yamada, T., et al.: Biochem. Pharmacol., 73, 981 (2007), Enman, J., et al.; J. Agric. Food Chem., 56, 2609 (2008),

• Brand: TRC

Chemical properties

• Molecular weight: 253.21
• Formula: C₉H₁₁N₅O₄
• Color/Form: Off White Solid
• InChI: InChI=1S/C9H11N5O4/c10-7-5-8(12-2-11-7)14(3-13-5)1-4(15)6(16)9(17)18/h2-4,6,15-16H,1H2,(H,17,18)(H2,10,11,12)/t4-,6-/m1/s1
• InChI key: InChIKey=LIEMBEWXEZJEEZ-INEUFUBQSA-N
• SMILES: Nc1ncnc2c1ncn2C[C@@H](O)[C@@H](O)C(=O)O