Erythromycin Cyclocarbonate

CAS: 55224-05-0

Ref. TR-E650045

Product Information

• Name: Erythromycin Cyclocarbonate
• Synonyms: 4H-1,3-Dioxolo[4,5-c]oxacyclotetradecin, erythromycin deriv., Davercin, Erythromycin A 11,12-carbonate, Erythromycin A cyclic 11,12-carbonate, Erythromycin cyclic carbonate, (1R,2R,5R,6S,7S,9R,11R,13R,14R)-8-[(2S,3R,4S,6R)-4-Dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-9-hydroxy-6-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-1,5,7,9,11,13-hexamethyl-3,15,17-trioxabicyclo[12.3.0]heptadecane-4,12,16-trione, (3aR,4R,7R,8S,9S,11R,13R,15R,15aR)-10-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4-ethyl-11-hydroxy-8-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3a,7,9,11,13,15-hexamethyloctahydro-4H-[1,3]dioxolo[4,5-c]oxacyclotetradecine-2,6,14(3aH,7H)-trione (non-preferred name), 4H-1,3-Dioxolo[4,5-c]oxacyclotetradecin, erythromycin deriv., Erythromycin, cyclic 11,12-carbonate

Description

Applications Erythromycin Cyclocarbonate is a derivative of Erythromycin (E649950), an antibcterial agent working on the 50S ribosomal subunit.
References Champney, W. et al.: Curr. Microbiol., 38, 342 (1999); Koch, W.L., et al.: Anal. Profiles Drug Subs., 8, 157 (1979),

• Brand: TRC

Chemical properties

• Molecular weight: 759.92
• Formula: C₃₈H₆₅NO₁₄
• Color/Form: Neat
• InChI: InChI=1S/C38H65NO14/c1-14-25-38(10)32(52-35(44)53-38)20(4)27(40)18(2)16-36(8,45)31(51-34-28(41)24(39(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-37(9,46-13)30(42)23(7)48-26/h18-26,28-32,34,41-42,45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30+,31-,32-,34+,36-,37-,38-/m1/s1
• InChI key: InChIKey=PHGMGTWRSNXLDV-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1ccc(C(=O)OCC)o1