Product Information
- a-[(3-Chlorophenyl)hydrazono]-5-(1,1-dimethylethyl)-ß-oxo-3-Isoxazolepropanenitrile
Applications ESI 09 acts as an EPAC inhibitor, preventing EPAC-mediated insulin release form β-pancreatic cells. Selective control for EPAC over PKA and decreases migration and invasion of AsPc-1 and PANC-1 pancreatic cancer cells.
References Tao, X. et al.: J. Virol., 88, 3902 (2014); Almahariq, M. et al.: Mol. Pharm., 83, 122 (2013);
Chemical properties
Technical inquiry about: TR-E658950 ESI 09
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