N-[2-(2-Ethoxyphenoxy)ethyl]-(R)-Tamsulosin

CAS: 918867-88-6

Ref. TR-E678605

Product Information

• Name: N-[2-(2-Ethoxyphenoxy)ethyl]-(R)-Tamsulosin
• Synonyms: 5-[(2R)-2-[Bis[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide, 5-((R)-2-[Bis-[2-(2-ethoxyphenoxy)ethyl]amino]propyl)-2-methoxybenzenesulfonamide, Tamsulosin EP Impurity A

Description

Impurity Tamsulosin EP Impurity A
Applications N-[2-(2-Ethoxyphenoxy)ethyl]-(R)-Tamsulosin (Tamsulosin EP Impurity A) is derived from 5-[(2R)-2-Aminopropyl]-2-methoxybenzenesulfonamide (A628695), which is a precursor in the synthesis of Tamsulosin (T006350) and other alpha-andregenic antagonists. (R)-Tamsulosin is a specific α1-adrenoceptor antagonist. It is used in the treatment of benign prostatic hypertrophy.
References Kawabe, K., et al.: J. Urol., 144, 908 (1990), Abrams, P., et al.: Br. J. Urol., 76, 325 (1995), Michel, M.C., Expert Opin. Pharmacother., 5, 151 (2004),

• Brand: TRC

Chemical properties

• Molecular weight: 572.71
• Formula: C₃₀H₄₀N₂O₇S
• Color/Form: Neat
• InChI: InChI=1S/C30H40N2O7S/c1-5-36-25-11-7-9-13-27(25)38-19-17-32(18-20-39-28-14-10-8-12-26(28)37-6-2)23(3)21-24-15-16-29(35-4)30(22-24)40(31,33)34/h7-16,22-23H,5-6,17-21H2,1-4H3,(H2,31,33,34)/t23-/m1/s1
• InChI key: InChIKey=OTXBFJHUSODSBC-HSZRJFAPSA-N
• SMILES: CCOc1ccccc1OCCN(CCOc1ccccc1OCC)[C@H](C)Cc1ccc(OC)c(S(N)(=O)=O)c1