Ethyl 2-[(5-Chloropyridin-2-yl)amino]-2-oxoacetate Hydrochloride

CAS: 1243308-37-3

Ref. TR-E702865

Product Information

• Name: Ethyl 2-[(5-Chloropyridin-2-yl)amino]-2-oxoacetate Hydrochloride
• Synonyms: 2-[(5-Chloropyridin-2-yl)amino]-2-oxoacetate Ethyl Ester Monohydrochloride, Ethyl 2-[(5-Chloropyridin-2-yl)amino]-2-oxoacetate Monohydrochloride, Acetic acid, 2-[(5-chloro-2-pyridinyl)aMino]-2-oxo-, ethyl ester, hydrochloride (1:1), 2-[(5-Chloropyridin-2-yl)amino]-2-oxoacetic acid ethyl ester monohydrochloride, 2-[(5-Chloropyridin-2-yl)amino]-2-oxoacetic acid ethyl ester HCl, 2-[(5-Chloropryidin-2-Yl)Amino]-2-Oxoacetic Acid Ethylester Monohydrochloride, Ethyl-2-[(5-chloropyridin-2-yl)amino]-2-oxoacetate hydrochloride
• CAS: 1243308-37-3

Description

Applications Ethyl 2-[(5-Chloropyridin-2-yl)amino]-2-oxoacetate Hydrochloride is an intermediate in the synthesis of Edoxaban-d6 (E555522), the isotope labelled analog of Edoxaban (E555520); an anticoagulant drug which acts as a direct factor Xa inhibitor.
References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)

• Brand: TRC

Chemical properties

• Molecular weight: 228.03017
• Formula: C₉H₉ClN₂O₃middot
• Color/Form: White Solid
• InChI: InChI=1S/C9H9ClN2O3.ClH/c1-2-15-9(14)8(13)12-7-4-3-6(10)5-11-7;/h3-5H,2H2,1H3,(H,11,12,13);1H
• InChI key: InChIKey=AZWJPQKNPCTYCU-UHFFFAOYSA-N
• SMILES: CCOC(=O)C(=O)Nc1ccc(Cl)cn1.Cl