N-Ethyl Maleimide

CAS: 128-53-0

Ref. TR-E817900

Product Information

• Name: N-Ethyl Maleimide
• Synonyms: 1-ethylpyrrole-2,5-dione, 1-Ethyl-1H-pyrrole-2,5-dione, 1-Ethyl-2,5-dihydro-1H-pyrrole-2,5-dione, Ethylmaleimide, Maleic acid N-ethylimide, Maleimide, N-ethyl-, N-Ethylmaleimid, N-Ethylmaleimide, N-etilmaleimida, NEM, Nsc 7638, 1H-Pyrrole-2,5-dione, 1-ethyl-, N-Ethylmaleimide, (NEM), 1-Ethyl-1H-pyrrole-2,5-dione~NEM

Description

Applications Reagent for the covalent modification of cysteine residues in proteins.NEM gives a clear solution in ethanol at 50 mg/ml. NEM dissolves in water (>50 mg in 4 ml); however, aqueous solutions are unstable. The rate of hydrolysis is pseudo-first order and significantly dependent on pH.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sheehan, M., et al.: J. Cell Biol., 106, 1 (1988), Vogel, K., et al.: J. Biol. Chem., 275, 2959 (2000), Ramos, C., et al.: Biochem. J., 400, 393 (2006),

• Brand: TRC

Chemical properties

• Molecular weight: 125.13
• Formula: C₆H₇NO₂
• Color/Form: Neat
• InChI: InChI=1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3
• InChI key: InChIKey=HDFGOPSGAURCEO-UHFFFAOYSA-N
• SMILES: CCN1C(=O)C=CC1=O