Estramustine Disodium Phosphate (~85%)

CAS: 52205-73-9

Ref. TR-E888983

Product Information

• Name: Estramustine Disodium Phosphate (~85%)
• Synonyms: Emcyt, Estracyt, Estramustine Phosphate Disodium, Estramustine Phosphate Disodium Salt, Estramustine Phosphate Sodium, Ro 21-8837/001, (17-Beta)-Estra-1,3,5(10)-Triene-3,17-Diol 3-(Bis(2-Chloroethyl)Carbamate) 17-(Dihydrogenphosphate) Disodium Salt, Disodium (17Beta)-3-{[Bis(2-Chloroethyl)Carbamoyl]Oxy}Estra-1,3,5(10)-Trien-17-Yl Phosphate, Estra-1,3,5(10)-triene-3,17-diol (17β)-, 3-[N,N-bis(2-chloroethyl)carbamate] 17-(dihydrogen phosphate), sodium salt (1:2), Estra-1,3,5(10)-triene-3,17-diol (17β)-, 3-[bis(2-chloroethyl)carbamate] 17-(dihydrogen phosphate), disodium salt, Estramustine disodium phosphate, Estramustine phosphate disodium, Estramustine phosphate disodium salt

Description

Stability Unstable in Solution
Applications Estramustine sodium phosphate is binds estradiol receptors irreversibly.
References Aurilio, G. et al.: Int. J. Clin. Oncol., 20, 90 (2015);

• Brand: TRC

Chemical properties

• Molecular weight: 564.35
• Formula: C₂₃H₃₀Cl₂NNa₂O₆P
• Purity: ~85%
• Color/Form: Neat
• InChI: InChI=1S/C23H32Cl2NO6P.2Na/c1-23-9-8-18-17-5-3-16(31-22(27)26(12-10-24)13-11-25)14-15(17)2-4-19(18)20(23)6-7-21(23)32-33(28,29)30;;/h3,5,14,18-21H,2,4,6-13H2,1H3,(H2,28,29,30);;/q;2*+1/p-2/t18-,19-,20+,21+,23+;;/m1../s1
• InChI key: InChIKey=IIUMCNJTGSMNRO-VVSKJQCTSA-L
• SMILES: C[C@]12CC[C@@H]3c4ccc(OC(=O)N(CCCl)CCCl)cc4CC[C@H]3[C@@H]1CC[C@@H]2OP(=O)(O[Na])O[Na]