7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin
CAS: 185304-42-1
Ref. TR-E899150
| 1mg | 335.00 € | ||
| 10mg | 1,328.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Product Information
Name:
7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin
Synonyms:
- 4-Amino-(4S)-4,11-diethyl-3,4,12,14-tetrahydro
- 4-Amino-(4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 1-Piperidinecarboxylic Acid Ester
- NPC (metabolite)
- Rpr 132595A
- (4S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 4-aminopiperidine-1-carboxylate
Description:
Stability Light Sensitive, Moisture Sensitive, Temperature Sensitive
Applications A major metabolite of Irinotecan.
References Canal, P., et al.: J. Clin. Oncol., 14, 2688 (1996), Haaz, M., et al.: Cancer Res., 58, 468 (1998), Kehrer, D., et al.: Clin. Cancer Res., 6, 3451 (2000), Hanioka, N., et al.: Xenobiotica, 31, 687 (2001), Satoh, T., et al.: Drug Metab. Dispos., 30, 488 (2002),
Notice:
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Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
518.56
Formula:
C28H30N4O6
Color/Form:
Neat
InChI:
InChI=1S/C28H30N4O6/c1-3-17-18-11-16(38-27(35)31-9-7-15(29)8-10-31)5-6-22(18)30-24-19(17)13-32-23(24)12-21-20(25(32)33)14-37-26(34)28(21,36)4-2/h5-6,11-12,15,36H,3-4,7-10,13-14,29H2,1-2H3/t28-/m0/s1
InChI key:
InChIKey=APWFTHDYKJHNEV-NDEPHWFRSA-N
SMILES:
CCc1c2c(nc3ccc(OC(=O)N4CCC(N)CC4)cc13)-c1cc3c(c(=O)n1C2)COC(=O)[C@]3(O)CC
MDL:
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EINECS:
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HS code:
Technical inquiry about: TR-E899150 7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin
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