7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin-d3

CAS: 1217625-98-3

Ref. TR-E899152

Product Information

• Name: 7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin-d3
• Synonyms: 4-Amino-(4S)-4-Ethyl-11-(ethyl-d3)-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 1-Piperidinecarboxylic Acid Ester, RPR 132595A-d3, NPC-d3 (metabolite)
• Brand: TRC
• Description: Applications A major labelled metabolite of Irinotecan.References Canal, P., et al.: J. Clin. Oncol., 14, 2688 (1996), Haaz, M., et al.: Cancer Res., 58, 468 (1998), Kehrer, D., et al.: Clin. Cancer Res., 6, 3451 (2000), Hanioka, N., et al.: Xenobiotica, 31, 687 (2001), Satoh, T., et al.: Drug Metab. Dispos., 30, 488 (2002),

Chemical properties

• Molecular weight: 521.58
• Formula: C₂₈D₃H₂₇N₄O₆
• Color/Form: Neat
• InChI: InChI=1S/C28H30N4O6/c1-3-17-18-11-16(38-27(35)31-9-7-15(29)8-10-31)5-6-22(18)30-24-19(17)13-32-23(24)12-21-20(25(32)33)14-37-26(34)28(21,36)4-2/h5-6,11-12,15,36H,3-4,7-10,13-14,29H2,1-2H3/t28-/m0/s1/i1D3
• InChI key: InChIKey=APWFTHDYKJHNEV-TVECXBKPSA-N
• SMILES: [2H]C([2H])([2H])Cc1c2c(nc3ccc(OC(=O)N4CCC(N)CC4)cc13)-c1cc3c(c(=O)n1C2)COC(=O)[C@]3(O)CC