13-O-Ethylamphotericin B (>80%)

Ref. TR-E899350

Product Information

• Name: 13-O-Ethylamphotericin B (>80%)
• Synonyms: (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-(((2R,3S,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1-ethoxy-3,5,6,9,11,17,37-heptahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic Acid
• Brand: TRC
• Description: Applications 13-O-Ethylamphotericin B is an analogue of 13-O-Methylamphotericin B (M287440), an antifungal. 13-O-Methylamphotericin B is a derivative of Amphotericin B (A634250), a polypeptide antibiotic active against gram positive bacteria. Antifungal.References Taylor, A.W., et. al.: J. Antibiot., 46, 486 (1993); Asher, I.M., et al.: Anal. Profiles Drug Subs., 6, 1, (1977)

Chemical properties

• Molecular weight: 952.13
• Formula: C₄₉H₇₇NO₁₇
• Purity: >80%
• Color/Form: Yellow To Orange
• InChI: InChI=1S/C49H77NO17/c1-6-63-49-27-35(53)24-38(55)37(54)22-21-33(51)23-34(52)25-41(57)64-31(4)30(3)44(58)29(2)19-17-15-13-11-9-7-8-10-12-14-16-18-20-36(26-40(67-49)42(47(61)62)39(56)28-49)66-48-46(60)43(50)45(59)32(5)65-48/h7-20,29-40,42-46,48,51-56,58-60H,6,21-28,50H2,1-5H3,(H,61,62)/b8-7+,11-9+,12-10+,15-13+,16-14+,19-17+,20-18+/t29-,30-,31-,32+,33+,34+,35-,36-,37+,38+,39-,40-,42+,43-,44+,45+,46-,48-,49+/m0/s1
• InChI key: InChIKey=XEMQZFXTPWVEJS-FOUHPWAISA-N
• SMILES: CCO[C@]12C[C@@H](O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)C[C@H](O1)[C@H](C(=O)O)[C@@H](O)C2