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(4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
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(4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione

CAS: 110351-94-5

Ref. TR-E917350

25mg
22,856.00 €
Estimated delivery in United States, on Monday 13 Jan 2025

Product Information

Name:
(4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
Controlled Product
Synonyms:
  • (4S)-4-hydroxy-4-propyl-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10-trione
Description:

Applications (4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione is a key intermediate in the synthesis of Irinotecan (I767500) and Camptothecin (C175150) analogs.
References Hsiang, Y., et al.: J. Biol. Chem., 260, 14873 (1985), Bao, Y., et al.: Chin. J. Med. Chem., 18, 263 (2008), Miao, Z., et al.: Bioorg. Med. Chem., 16, 1493 (2008),

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
277.273
Formula:
C14H15NO5
Color/Form:
Neat
InChI:
InChI=1S/C14H15NO5/c1-2-4-14(19)9-6-10-11(16)3-5-15(10)12(17)8(9)7-20-13(14)18/h6,19H,2-5,7H2,1H3/t14-/m0/s1
InChI key:
InChIKey=IGKWOGMVAOYVSJ-ZDUSSCGKSA-N
SMILES:
CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)CCC1=O
MDL:
Melting point:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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