1-N-Ethylgaramine Sulfate

CAS: 864371-49-3

Ref. TR-E918350

Product Information

• Name: 1-N-Ethylgaramine Sulfate
• Synonyms: 2-Deoxy-6-O-[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]-N1-ethyl-D-streptamine Sulfate Salt

Description

Stability Hygroscopic
Applications 1-N-Ethylgaramine sulfate is a derivative of Garamine (triacetate salt: G245300), an impurity of Gentamicin (G360600). Gentamicin is a widely used aminoglycoside antibiotic that is toxic to the kidney and the inner ear.
References Carlier, M., et al.: Biochem. Pharmacol., 31, 3861 (1982); Von Ahsen, U., et al.: J. Mol. Biol., 226, 935 (1992), Grahek, R., et al.: J. Pharm. Biomed. Anal., 50, 1037 (2009); Sha, S. & Schacht, J.: Lab. Invest., 79, 807 (1999)

• Brand: TRC

Chemical properties

• Molecular weight: 349.42 + x(98.08)
• Formula: C₁₅H₃₁N₃O₆·xH₂SO₄
• Color/Form: Neat
• InChI: InChI=1S/C15H31N3O6/c1-4-18-8-5-7(16)9(19)10(20)12(8)24-14-11(21)13(17-3)15(2,22)6-23-14/h7-14,17-22H,4-6,16H2,1-3H3/t7-,8-,9-,10-,11-,12-,13-,14-,15+/m1/s1
• InChI key: InChIKey=NYPNSRUEPMFDBL-WRJVUQEZSA-N
• SMILES: CCN[C@@H]1C[C@@H](N)[C@@H](O)[C@@H](O)[C@@H]1O[C@H]1OC[C@](C)(O)[C@H](NC)[C@H]1O