Ethyl Malonyl Chloride

CAS: 36239-09-5

Ref. TR-E922050

Product Information

• Name: Ethyl Malonyl Chloride
• Synonyms: (Chlorocarbonyl)acetic Acid Ethyl Ester, (Chloroformyl)acetic Acid Ethyl Ester, (Ethoxycarbonyl)acetyl Chloride, 2-(Ethoxycarbonyl)acetyl Chloride, 3-Chloro-3-oxopropanoic Acid Ethyl Ester, 3-Ethoxy-3-oxopropanoyl Chloride, Carbethoxyacetyl Chloride, Carbethoxyethanoyl Chloride, Carboethoxyacetyl Chloride, Ethoxymalonyl Chloride, Ethyl (Chlorocarbonyl)acetate, Ethyl (Chloroformyl)acetate, Ethyl 3-Chloro-3-oxopropanoate, Ethyl 3-Chloro-3-oxopropionate, Ethyl 3-Oxo-3-chloropropanoate, Ethyl Malonoyl Chloride, Malonic Acid Chloride Ethyl Ester, Malonic acid chloride monoethyl ester, (Chlorocarbonyl)acetic acid ethyl ester, (Chloroformyl)Acetic Acid Ethyl Ester, (Ethoxycarbonyl)acetyl chloride, 2-(Ethoxycarbonyl)acetyl chloride, 3-Chloro-3-Oxo-Propanoicaciethylester, 3-Chloro-3-oxopropanoic acid ethyl ester, 3-Ethoxy-3-oxopropanoyl chloride, Acetic acid, (chloroformyl)-, ethyl ester, Aurora Ka-3051, Carbethoxyacetyl chloride, Carbethoxyethanoyl chloride, Carboethoxyacetyl chloride, Ethanyl Malonyl Chloride, Ethoxymalonyl chloride, Ethyl (chlorocarbonyl)acetate, Ethyl 2-(Chlorocarbonyl)Acetate, Ethyl 3-Chloro-3-Oxopropionate, Ethyl 3-chloro-3-oxopropanoate, Ethyl 3-oxo-3-chloropropanoate, Ethyl malonoyl chloride, Ethyl malonyl monochloride, Ethyl(chloroformyl)acetate, Ethylpropanedioyl Dichloride, Malonic acid chloride ethyl ester, Malonic acid ethyl ester chloride, Malonic acid monoethyl ester chloride, Malonic chloride ethyl ester, Malonic ethyl ester chloride, Monoethyl malonyl chloride, Propanoic acid, 3-chloro-3-oxo-, ethyl ester

Description

Stability Moisture Sensitive
Applications Ethyl Malonyl Chloride is used as a reagent in the synthesis of novel thiadiazoloacrylamide analogs as inhibitors of dengue-2 virus NS2B/NS3 protease. Ethyl Malonyl Chloride is also used as a reagent in the synthesis of quinolone-benzylpiperidine derivatives as acetylcholinesterase inhibitors and antioxidant hybrids for Alzheimer disease.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Liu, H., et al.: Bioorg. Med. Chem., 22, 6344 (2014); Pudlo, M., et al.: Bioorg. Med. Chem., 22, 2496 (2014)

• Brand: TRC

Chemical properties

• Molecular weight: 150.56
• Formula: C₅H₇ClO₃
• Color/Form: Neat
• InChI: InChI=1S/C5H7ClO3/c1-2-9-5(8)3-4(6)7/h2-3H2,1H3
• InChI key: InChIKey=KWFADUNOPOSMIJ-UHFFFAOYSA-N
• SMILES: CCOC(=O)CC(=O)Cl