Ethyl Malonyl Chloride

CAS: 36239-09-5

Ref. TR-E922050

Product Information

• Name: Ethyl Malonyl Chloride
• Synonyms: (Chlorocarbonyl)acetic Acid Ethyl Ester, (Chloroformyl)acetic Acid Ethyl Ester, (Ethoxycarbonyl)acetyl Chloride, 2-(Ethoxycarbonyl)acetyl Chloride, 3-Chloro-3-oxopropanoic Acid Ethyl Ester, 3-Ethoxy-3-oxopropanoyl Chloride, Carbethoxyacetyl Chloride, Carbethoxyethanoyl Chloride, Carboethoxyacetyl Chloride, Ethoxymalonyl Chloride, Ethyl (Chlorocarbonyl)acetate, Ethyl (Chloroformyl)acetate, Ethyl 3-Chloro-3-oxopropanoate, Ethyl 3-Chloro-3-oxopropionate, Ethyl 3-Oxo-3-chloropropanoate, Ethyl Malonoyl Chloride, Malonic Acid Chloride Ethyl Ester
• Brand: TRC
• Description: Stability Moisture SensitiveApplications Ethyl Malonyl Chloride is used as a reagent in the synthesis of novel thiadiazoloacrylamide analogs as inhibitors of dengue-2 virus NS2B/NS3 protease. Ethyl Malonyl Chloride is also used as a reagent in the synthesis of quinolone-benzylpiperidine derivatives as acetylcholinesterase inhibitors and antioxidant hybrids for Alzheimer disease. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Liu, H., et al.: Bioorg. Med. Chem., 22, 6344 (2014); Pudlo, M., et al.: Bioorg. Med. Chem., 22, 2496 (2014)

Chemical properties

• Molecular weight: 150.56
• Formula: C₅H₇ClO₃
• Color/Form: Neat
• InChI: InChI=1S/C5H7ClO3/c1-2-9-5(8)3-4(6)7/h2-3H2,1H3
• InChI key: InChIKey=KWFADUNOPOSMIJ-UHFFFAOYSA-N
• SMILES: CCOC(=O)CC(=O)Cl