Ethyl N-Methyl-b-alaninate

CAS: 2213-08-3

Ref. TR-E923360

Product Information

• Name: Ethyl N-Methyl-b-alaninate
• Synonyms: 3-(Methylamino)propanoic Acid Ethyl Ester, 3-(Methylamino)propionic Acid Ethyl Ester, Ethyl 3-(Methylamino)propanoate, Ethyl 3-(Methylamino)propionate, Ethyl N-Methyl-beta-alaninate, Ethyl beta-(Methylamino)propionate, N-Methyl-beta-alanine Ethyl Ester, N-[2-(Ethoxycarbonyl)ethyl]-N-methylamine, .beta.-Alanine, N-methyl-, ethyl ester, 3-(Methylamino)propionic acid ethyl ester, Ethyl 3-(methylamino)propanoate, Ethyl N-methyl-beta-alaninate

Description

Applications Ethyl N-Methyl-beta-alaninate is an intermediate in the synthesis of Tolafentrine (T531000), which is a dual-selective phosphodiesterase 3/4 inhibitor used in chronic experimental pulmonary hypertension.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Huxtable, R., et al.: Pharmacol. Ther., 47, 371 (1990), Tanaka, K., et al.: Cancer Res., 55, 2927 (1995), Wagner, R., et al.: J. Pharmacol. Exp. Ther., 282, 1650 (1997), Cowan, K., et al.: Nat. Med., 6, 698 (2000), Shankavaram, U., et al.: J. Biol. Chem., 276, 19027 (2001),

• Brand: TRC

Chemical properties

• Molecular weight: 131.17
• Formula: C₆H₁₃NO₂
• Color/Form: Neat
• InChI: InChI=1S/C6H13NO2/c1-3-9-6(8)4-5-7-2/h7H,3-5H2,1-2H3
• InChI key: InChIKey=XVIJMHJTEHBUJI-UHFFFAOYSA-N
• SMILES: CCOC(=O)CCNC