5-Ethyl-3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-1H-indole

CAS: 209682-64-4

Ref. TR-E924900

Product Information

• Name: 5-Ethyl-3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-1H-indole
• Synonyms: Eletriptan Impurity
• Brand: TRC

Description

Impurity Eletriptan Impurity
Applications 5-Ethyl-3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-1H-indole is an impurity of Eletriptan (E505000), a serotonin 5-HTIB/ID receptor agonist and an antimigraine agent.
References Madasu, S. B., et al.: Beilstein. J. Org. Chem., 8, 1400 (2012); Willems, E., et al.: Arch. Pharmacol., 358, 212 (1998), Napier, C., et al.: Eur. J. Pharmacol., 368, 259 (1999), Goadsby, P.J., et al.: Neurology, 54, 156 (2000)

Chemical properties

• Molecular weight: 242.36
• Formula: C₁₆H₂₂N₂
• Color/Form: Neat
• InChI: InChI=1S/C16H22N2/c1-3-12-6-7-16-15(9-12)13(11-17-16)10-14-5-4-8-18(14)2/h6-7,9,11,14,17H,3-5,8,10H2,1-2H3/t14-/m1/s1
• InChI key: InChIKey=XQBUOODGXPTQOQ-CQSZACIVSA-N
• SMILES: CCc1ccc2[nH]cc(C[C@H]3CCCN3C)c2c1