Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate

CAS: 157307-36-3

Ref. TR-E925345

Product Information

• Name: Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate
• Synonyms: Dutasteride EP Impurity C, ethyl (4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylate, 1H-Indeno[5,4-f]quinoline-7-carboxylic acid, 2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, ethyl ester, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-, 4-Azaandrost-1-ene-17-carboxylic acid, 3-oxo-, ethyl ester, (5a,17ß)-, 1H-Indeno[5,4-f]quinoline, 4-azaandrost-1-ene-17-carboxylic acid deriv., Ethyl 3-oxo-4-aza-5a-androst-1-ene-17ß-carboxylate, 3-Oxo-4-aza-5a-androst-1-ene-17ß-carboxylic Acid Ethyl Ester, Dutasteride Imp C (EP), Dutasteride Ethyl Ester, Dutasteride Impurity C

Description

Impurity Dutateride EP Impurity C
Applications Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate (Dutateride EP Impurity C) is a compound synthesized in the production of azasteroids. Used in the inhibition of 5α-reductase and of androgen receptor binding, both major effecters in the male hormonal system.
References Ramusson, G. et al.: J. Med. Chem., 29, 2298 (1986);

• Brand: TRC

Chemical properties

• Molecular weight: 345.48
• Formula: C₂₁H₃₁NO₃
• Color/Form: White To Off-White
• InChI: InChI=1S/C21H31NO3/c1-4-25-19(24)16-7-6-14-13-5-8-17-21(3,12-10-18(23)22-17)15(13)9-11-20(14,16)2/h10,12-17H,4-9,11H2,1-3H3,(H,22,23)/t13-,14-,15-,16+,17+,20-,21+/m0/s1
• InChI key: InChIKey=AHSRUURQZYMTKR-FKLRSJPUSA-N
• SMILES: CCOC(=O)[C@H]1CCC2C3CC[C@H]4NC(=O)C=C[C@]4(C)C3CC[C@@]21C