5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-methylene]-2,4-thiazolidinedione(Pioglitazone Impurity)

CAS: 144809-28-9

Ref. TR-E925590

Product Information

• Name: 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-methylene]-2,4-thiazolidinedione(Pioglitazone Impurity)
• Synonyms: 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-, 5-[[4-[2-(5-Ethyl-2-pyridyl)ethoxy]phenyl]methylene]thiazolidine-2,4-dione
• Brand: TRC

Description

Impurity Pioglitazone EP Impurity B
Applications 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-methylene]-2,4-thiazolidinedione (Pioglitazone EP Impurity B) is a novel intermediate of Pioglitazone (P471000).
References Diaz, J., et al.: J. Biol. Chem., 272, 11350 (1997), Day, C., et al.: Diabet Med., 16, 179 (1999), Motomura, W., et al.: Cancer Res., 60, 5558 (2000), Koeffler, H., et al.: Clin. Cancer Res., 9, 1 (2003),

Chemical properties

• Molecular weight: 354.42
• Formula: C₁₉H₁₈N₂O₃S
• Color/Form: Neat
• InChI: InChI=1S/C19H18N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,11-12H,2,9-10H2,1H3,(H,21,22,23)/b17-11+
• InChI key: InChIKey=YNTUJOCADSTMCL-GZTJUZNOSA-N
• SMILES: CCc1ccc(CCOc2ccc(/C=C3/SC(=O)NC3=O)cc2)nc1