Product Information
Name:5-Ethynyl-2’-deoxyuridine
Controlled Product
Synonyms:
- EdU
- 2'-Deoxy-5-ethynyluridine
Brand:TRC
Description:
Applications 5-Ethynyl-2’-deoxyuridine is an extensively used nucleoside analog used as a probe for DNA synthesis. 5-Ethynyl-2’-deoxyuridine is known as an toxic anti-metabolite, which potentially causes DNA instabiliy, necrosis and cell-cycle arrest, therefore it is often used for short-term DNA synthesis in tissue culture and living organisms where prolonged cell survival is not required.
References Neef, A.B., et al.: P. Natl. Acad. Sci.., 108, 20404 (2011); Gristwood, T., et al.: Nucleic. Acids. Rsch., 40, 5487 (2012);
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:252.22
Formula:C11H12N2O5
Color/Form:Neat
InChI:InChI=1S/C11H12N2O5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h1,4,7-9,14-15H,3,5H2,(H,12,16,17)/t7-,8+,9+/m0/s1
InChI key:InChIKey=VNWKTOKETHGBQD-UHFFFAOYSA-N
SMILES:C#Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)nc1O
Technical inquiry about: 5-Ethynyl-2’-deoxyuridine
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