Estimated delivery in United States, on Tuesday 25 Jun 2024
Product Information
Name:
EW 7197
Synonyms:
- N-[[4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]-2-fluoroaniline
- N-?(2-?Fluorophenyl)?-?5-?(6-?methyl-?2-?pyridinyl)?-?4-?[1,?2,?4]?triazolo[1,?5-?a]?pyridin-?6-?yl-1H-?imidazole-?2-?methanamine
CAS:
Description:
Applications EW-7197 is a highly potent, selective, and orally bioavailable TGF-β I receptor ALK4/ALK5 inhibitor.
References Jin, C., et al.: J. Med. Chem., 57, 4213 (2014); Yoon, J., et al.: EMBO Mol. Med., 5, 1720 (2013); Son, J., et al.: Mol. Cancer Ther., 13, 1704 (2014)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
399.42
Formula:
C22H18FN7
Color/Form:
Neat
InChI:
InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2
InChI key:
InChIKey=FVYXIJYOAGAUQK-UHFFFAOYSA-N
SMILES:
C=CCc1ccc(O)c(-c2ccc(O)c(CC=C)c2)c1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-E950000 EW 7197
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