CAS 1352608-82-2

EW-7197

Description:

EW-7197, identified by its CAS number 1352608-82-2, is a chemical compound that has garnered attention in the field of medicinal chemistry, particularly for its potential therapeutic applications. It is characterized by its specific molecular structure, which includes various functional groups that contribute to its biological activity. The compound is typically studied for its role in modulating certain biological pathways, making it a candidate for drug development. Its solubility, stability, and reactivity are important characteristics that influence its efficacy and safety profile in biological systems. Additionally, EW-7197 may exhibit unique pharmacokinetic properties, affecting its absorption, distribution, metabolism, and excretion in living organisms. Research into this compound may also explore its interactions with specific receptors or enzymes, providing insights into its mechanism of action. Overall, EW-7197 represents a significant area of interest for researchers aiming to develop new therapeutic agents.

Formula: C22H18FN7

InChI: InChI=1S/C22H18FN7/c1-14-5-4-8-18(27-14)22-21(15-9-10-20-25-13-26-30(20)12-15)28-19(29-22)11-24-17-7-3-2-6-16(17)23/h2-10,12-13,24H,11H2,1H3,(H,28,29)

InChI key: FJCDSQATIJKQKA-UHFFFAOYSA-N

SMILES: CC1=NC(=CC=C1)C2=C(N=C(N2)CNC3=CC=CC=C3F)C4=CN5C(=NC=N5)C=C4

N-((4-([1,2,4]Triazolo[1,5-A]Pyridin-6-Yl)-5-(6-Methylpyridin-2-Yl)-1H-Imidazol-2-Yl)Methyl)-2-Fluoroaniline

CAS: 1352608-82-2

N-((4-([1,2,4]Triazolo[1,5-A]Pyridin-6-Yl)-5-(6-Methylpyridin-2-Yl)-1H-Imidazol-2-Yl)Methyl)-2-Fluoroaniline

Formula: C₂₂H₁₈FN₇

Purity: 98%

Molecular weight: 399.42

Ref: 54-PC108976

Vactosertib

CAS: 1352608-82-2

Vactosertib

Formula: C₂₂H₁₈FN₇

Purity: ≥98%

Molecular weight: 399.42

Ref: 54-BUP15008

Vactosertib

CAS: 1352608-82-2

N-((4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-fluoroaniline

Formula: C₂₂H₁₈FN₇

Purity: 98%

Molecular weight: 399.42

Ref: IN-DG305563

Vactosertib

CAS: 1352608-82-2

Vactosertib (EW-7197) is an oral TGFBR1/ALK5 inhibitor with potential cancer-fighting properties.

Formula: C₂₂H₁₈FN₇

Purity: 98.85% - 99.81%

Color and Shape: White Solid

Molecular weight: 399.4236

Ref: TM-T6496

2-fluoro-N-{[4-(6-methylpyridin-2-yl)-5-{[1,2,4]triazolo[1,5-a]pyridin-6-yl}-1H-imidazol-2-yl]methyl}aniline

CAS: 1352608-82-2

Purity: 98%

Molecular weight: 399.4330139

Ref: 10-F862530

EW 7197

Controlled Product

CAS: 1352608-82-2

Applications EW-7197 is a highly potent, selective, and orally bioavailable TGF-β I receptor ALK4/ALK5 inhibitor.
References Jin, C., et al.: J. Med. Chem., 57, 4213 (2014); Yoon, J., et al.: EMBO Mol. Med., 5, 1720 (2013); Son, J., et al.: Mol. Cancer Ther., 13, 1704 (2014)

Formula: C₂₂H₁₈FN₇

Color and Shape: Neat

Molecular weight: 399.42

Ref: TR-E950000

TEW 7197

CAS: 1352608-82-2

TGF-? type I receptor antagonist; anti-cancer agent

Formula: C₂₂H₁₈FN₇

Purity: Min. 95%

Molecular weight: 399.42 g/mol

Ref: 3D-BT168124

N-[[4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]-2-fluoroaniline

CAS: 1352608-82-2

Formula: C₂₂H₁₈FN₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 399.4236

Ref: IN-DA003AC8