(Z)-Ethyl 4-(2-(tert-Butoxy)-2-oxoethoxy)-2-(2-chlorobenzylidene)-3-oxobutanoate
Ref. TR-E951860
100mg
1,530.00€
Product Information
Name:(Z)-Ethyl 4-(2-(tert-Butoxy)-2-oxoethoxy)-2-(2-chlorobenzylidene)-3-oxobutanoate
Controlled Product
Synonyms:
- ethyl (2Z)-2-[(2-chlorophenyl)methylidene]-4-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethoxy]-3-oxobutanoate
Brand:TRC
Description:Applications (Z)-Ethyl 4-(2-(tert-butoxy)-2-oxoethoxy)-2-(2-chlorobenzylidene)-3-oxobutanoate is an intermediate for the synthesis of O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine (D289480), which is the metablolite of Amlodipine (A633495), a long-acting calcium channel blocker that is commonly used as an anti-hypertensive in the treatment of cardiovascular conditions.References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986), Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1987), Haria, M., et al.: Drugs, 50, 560 (1995)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:382.835
Formula:C19H23ClO6
Color/Form:Neat
InChI:InChI=1S/C19H23ClO6/c1-5-25-18(23)14(10-13-8-6-7-9-15(13)20)16(21)11-24-12-17(22)26-19(2,3)4/h6-10H,5,11-12H2,1-4H3/b14-10-
InChI key:InChIKey=DQIJJTDIMMDERW-UVTDQMKNSA-N
SMILES:CCOC(=O)/C(=C\c1ccccc1Cl)C(=O)COCC(=O)OC(C)(C)C
Technical inquiry about: (Z)-Ethyl 4-(2-(tert-Butoxy)-2-oxoethoxy)-2-(2-chlorobenzylidene)-3-oxobutanoate
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