(3R,4S)-3-[(3S)-3-(4-Fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-(2,3,5,6-tetradeuterio-4-fluorophenyl)azetidin-2-one

CAS: 1093659-90-5

Ref. TR-E975002

Product Information

• Name: (3R,4S)-3-[(3S)-3-(4-Fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-(2,3,5,6-tetradeuterio-4-fluorophenyl)azetidin-2-one
• Synonyms: (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl-2,3,5,6-d4)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone, Ezetimibe-d4, Ezetimibe-D4 (N-(4-fluorophenyl-D4)), Ezetimibe-d4 [N-(4-fluorophenyl-d4)]
• Brand: TRC
• Description: Applications Labelled Ezetimibe (E975000), an antihyperlipoproteinemic. A Cholesterol absorption inhibitor.References van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997), van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)

Chemical properties

• Molecular weight: 413.45
• Formula: C₂₄₂H₄H₁₇F₂NO₃
• Color/Form: Neat
• InChI: InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1/i7D,8D,9D,10D
• InChI key: InChIKey=OLNTVTPDXPETLC-ARVCERDTSA-N
• SMILES: [2H]c1c([2H])c(N2C(=O)[C@H](CC[C@H](O)c3ccc(F)cc3)[C@H]2c2ccc(O)cc2)c([2H])c([2H])c1F