Fenretinide

CAS: 65646-68-6

Ref. TR-F250000

Product Information

• Name: Fenretinide
• Synonyms: (2E,4E,6E,8E)-N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenamide, (4-Hydroxyphenyl)retinamide, 15-[(4-Hydroxyphenyl)Amino]Retinal, 4-Hpr, Mk 4016, N-(4-hydroxyphenyl)all-trans retinamide, RII retinamide, Retinamide, N-(4-hydroxyphenyl)-, Retinoic acid p-hydroxyanilide, Retinoic acid p-hydroxyphenylamide, Ro 22-4667, all-trans-4′-Hydroxyretinanilide, all-trans-N-(4-hydroxyphenyl)retinamide
• CAS: 65646-68-6

Description

Stability Light Sensitive - Protect from Light Exposure
Applications Fenretinide (4-HPR) is a synthetic retinoid deriverative. 4-HBR is shown to exhibit binding to the retinoic acid receptors (RAR) at concentrations necessary to induce cell death.A synthetic analog of Vitamin A.
References Marth, C., et al.:J. Nat. Cancer Inst., 75, 871 (1985), Delia, D., et al.: Cancer Res., 53, 6036 (1993), Costa., A., et al.: Cancer Res., 54, Suppl., 2032s (1994), Decensi., A., et al.: Eur. J. Cancer Prev., 3, 377 (1994)

• Brand: TRC

Chemical properties

• Molecular weight: 391.55
• Formula: C₂₆H₃₃NO₂
• Color/Form: Neat
• InChI: InChI=1S/C26H33NO2/c1-19(11-16-24-21(3)10-7-17-26(24,4)5)8-6-9-20(2)18-25(29)27-22-12-14-23(28)15-13-22/h6,8-9,11-16,18,28H,7,10,17H2,1-5H3,(H,27,29)/b9-6+,16-11+,19-8+,20-18+
• InChI key: InChIKey=AKJHMTWEGVYYSE-YMRZRNJCSA-N
• SMILES: CC1=C(/C=C\C(C)=C\C=C/C(C)=C\C(=O)Nc2ccc(O)cc2)C(C)(C)CCC1