Flavokavain B

CAS: 1775-97-9

Ref. TR-F371025

Product Information

• Name: Flavokavain B
• Synonyms: 2'-Hydroxy-4',6'-dimethoxychalcone, (2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-phenyl-2-propen-1-one, (2E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenylprop-2-en-1-one, (E)-1-(2-Hydroxy-4,6-Dimethoxy-Phenyl)-3-Phenyl-Propenone, (E)-1-(2-Hydroxy-4,6-dimethoxy-phenyl)-3-phenyl-, (E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-phenylprop-2-en-1-one, (E)-2′-Hydroxy-4′,6′-dimethoxychalcone, 1-(2-Hydroxy-4,6-Dimethoxyphenyl)-3-Phenyl-2-Propen-1-One), 2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenyl-, (2E)-, 2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenyl-, (E)-, Cardamonin-4'-Methyl Ether, Chalcone, 2′-hydroxy-4′,6′-dimethoxy-, Dimethoxy-2'-Hydroxychalcone, 4',6'-, Flavokavin B, Flavokawain B, Flavokawin B, Persicochalcone

Description

Applications Flavokavain B is a secondary metabolite of the kava plant (Piper methysticum Forst. f., Piperaceae, which has anticancer properties and demonstrated oral efficacy in murine cancer models. Futhermore, it also has suspected roles in rare cases of kava-induced hepatotoxicity. In addition, it is a potential candidate for the development of novel antifungal phytotherapic products.
References Pinner, K. D., et al.: Pharmaceutical Biology (Abingdon, United Kingdom), 54, Epub ahead of print (2016); Rowe A., et al.: Phytotherapy Research, 26, 1768 (2012); Alves dos Santos, R., et al.: Journal of Chemistry, (2013)

• Brand: TRC

Chemical properties

• Molecular weight: 284.31
• Formula: C₁₇H₁₆O₄
• Color/Form: Yellow To Dark Yellow
• InChI: InChI=1S/C17H16O4/c1-20-13-10-15(19)17(16(11-13)21-2)14(18)9-8-12-6-4-3-5-7-12/h3-11,19H,1-2H3/b9-8+
• InChI key: InChIKey=QKQLSQLKXBHUSO-CMDGGOBGSA-N
• SMILES: COc1cc(O)c(C(=O)/C=C/c2ccccc2)c(OC)c1