Fumaric Acid tert-Butyl Ester (>90%)

CAS: 135355-96-3

Ref. TR-F500395

Product Information

• Name: Fumaric Acid tert-Butyl Ester (>90%)
• Synonyms: (2E)-2-Butenedioic Acid Mono(1,1-dimethylethyl) Ester, (E)-4-tert-Butoxy-4-oxobut-2-enoic Acid
• Brand: TRC
• Description: Applications Fumaric Acid tert-Butyl Ester is a tert-Butyl ester derivative of Fumaric Acid (F500380). Fumaric Acid tert-Butyl Ester is a reactant used in the preparation of cysteine protease inhibitors based on fumaric acid-derived oligopeptides. It is also used in the preparation of Nε-fumaroylated diketopiperazine of L-Lys used for pulmonary drug delivery.References Breuning, A. et al.: J. Med. Chem., 53, 1951 (2010); Machon, U. et al.: J. Med. Chem., 52, 5662 (2009)

Chemical properties

• Molecular weight: 172.18
• Formula: C₈H₁₂O₄
• Purity: >90%
• Color/Form: Neat
• InChI: InChI=1S/C8H12O4/c1-8(2,3)12-7(11)5-4-6(9)10/h4-5H,1-3H3,(H,9,10)/b5-4+
• InChI key: InChIKey=BAXKSCVINAKVNE-SNAWJCMRSA-N
• SMILES: CC(C)(C)OC(=O)/C=C/C(=O)O