Fluocortolone

CAS: 152-97-6

Ref. TR-F500500

Product Information

• Name: Fluocortolone
• Synonyms: Pregna-1,4-diene-3,20-dione, 6-fluoro-11,21-dihydroxy-16-methyl-, (6a,11ß,16a)-, Pregna-1,4-diene-3,20-dione, 6a-fluoro-11ß,21-dihydroxy-16a-methyl- (7CI,8CI), 16a-Methyl-6a-fluoro-?1,4-pregnadien-11ß,21-diol-3,20-dione, 6a-Fluoro-11ß,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione, 6a-Fluoro-16a-methyl-1,4-pregnadiene-11ß,21-diol-3,20-dione, 6a-Fluoro-16a-methyl-?1,4-pregnadiene-11ß,21-diol-3,20-dione, 6a-Fluoro-16a-methyl-?1-corticosterone, Flucortolone, Fluocortolon, SH 742, Ultralan oral, (6Alpha,11Beta,16Alpha)-6-Fluoro-11,21-Dihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione, (6α,11β,16α)-6-Fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, 16α-Methyl-6α-fluoro-Δ^1,4-pregnadien-11β,21-diol-3,20-dione, 6-Alpha-Fluoro-11-Beta,21-Dihydroxy-16-Alpha-Methylpregna-1,4-Diene-3,20-Dione, 6α-Fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione, 6α-Fluoro-16α-methyl-1,4-pregnadiene-11β,21-diol-3,20-dione, 6α-Fluoro-16α-methyl-Δ^1,4-pregnadiene-11β,21-diol-3,20-dione, 6α-Fluoro-16α-methyl-Δ¹-corticosterone, Methylfluorodehydrocorticosterone, Pregna-1,4-diene-3,20-dione, 6-fluoro-11,21-dihydroxy-16-methyl-, (6α,11β,16α)-, Pregna-1,4-diene-3,20-dione, 6α-fluoro-11β,21-dihydroxy-16α-methyl-, Sh 742

Description

Applications Fluocortolone is a glucocorticoid used in the treatment of several conditions, including hemorrhoids. Fluocortolone is similar to Fluocortin, but with one less keto group.
References Breuer, et al.: Arzneim.-Forsch., 15, 50 (1965), Domenico, et al.: Arzneim.-Forsch., 15, 46 (1965), Gerhards, et al.: Acta Endocrinol., 68, 98 (1971),

• Brand: TRC

Chemical properties

• Molecular weight: 376.46
• Formula: C₂₂H₂₉FO₄
• Color/Form: Off-White To Yellow
• InChI: InChI=1S/C22H29FO4/c1-11-6-14-13-8-16(23)15-7-12(25)4-5-21(15,2)20(13)17(26)9-22(14,3)19(11)18(27)10-24/h4-5,7,11,13-14,16-17,19-20,24,26H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19-,20-,21+,22+/m1/s1
• InChI key: InChIKey=GAKMQHDJQHZUTJ-ULHLPKEOSA-N
• SMILES: C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]2(C)[C@H]1C(=O)CO