(11Beta)-9-Fluoro-11,21-dihydroxy-16-methyl-pregna-1,4,16-triene-3,20-dione

CAS: 59860-99-0

Ref. TR-F591115

Product Information

• Name: (11Beta)-9-Fluoro-11,21-dihydroxy-16-methyl-pregna-1,4,16-triene-3,20-dione
• Synonyms: Pregna-1,4,16-triene-3,20-dione, 9-fluoro-11,21-dihydroxy-16-methyl-, (11β)-, (11β)-9-Fluoro-11,21-dihydroxy-16-methylpregna-1,4,16-triene-3,20-dione, 9-Fluoro-11β,21-dihydroxy-16-methylpregna-1,4,16-triene-3,20-dione, 9-Fluoro-11beta,21-dihydroxy-16-methylpregna-1,4,16-triene-3,20-dione, Pregna-1,4,16-triene-3,20-dione, 9-fluoro-11,21-dihydroxy-16-methyl-, (11β)-, (11β)-9-Fluoro-11,21-dihydroxy-16-methylpregna-1,4,16-triene-3,20-dione, 9-Fluoro-11β,21-dihydroxy-16-methylpregna-1,4,16-triene-3,20-dione
• Brand: TRC

Description

Applications (11β)-9-Fluoro-11,21-dihydroxy-16-methyl-pregna-1,4,16-triene-3,20-dione is a derivative of Dexamethasone (D298800), an anti-inflammatory glucocorticoid.
References Kodelja, V., et al.: J. Immunol., 160, 1411 (1998), Metselaar, J., et al.: Arthritis Rheum., 48, 2059 (2003), Buttgereit, F., et al.: Arthritis Rheum., 50, 3408 (2004), Martinez, F., et al.: Front Biosci., 13, 453 (2008),

Chemical properties

• Molecular weight: 374.45
• Formula: C₂₂H₂₇FO₄
• Color/Form: Neat
• InChI: InChI=1S/C22H27FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,15-16,18,24,27H,4-5,8,10-11H2,1-3H3/t15-,16-,18-,20-,21-,22-/m0/s1
• InChI key: InChIKey=PSXDNQUHAFMVPT-QEYSUVLUSA-N
• SMILES: CC1=C(C(=O)CO)[C@@]2(C)C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]2C1