9-Fluoro-16α,17-(isopropylidenedioxy) Corticosterone

CAS: 1524-86-3

Ref. TR-F592050

Product Information

• Name: 9-Fluoro-16α,17-(isopropylidenedioxy) Corticosterone
• Synonyms: (11ß,16a)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregn-4-ene-3,20-dione, Corticosterone, 9-fluoro-16a,17-dihydroxy-, cyclic 16,17-acetal with Me2CO (6CI), Pregn-4-ene-3,20-dione, 9-fluoro-11ß,16a,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone (7CI,8CI), (11ß,16a)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregn-4-ene-3,20-dione, 2H-Naphth[2',1':4,5]indeno[1,2-d][1,3]dioxole, pregn-4-ene-3,20-dione deriv., 11ß,16a,17a,21-Tetrahydroxy-9a-fluoropregn-4-ene-3,20-dione 16,17-acetonide, NSC 21915, 1,2-Dihydrotriamcinolone Acetonide, Triamcinolone Acetonide Imp. E (EP), (11β,16α)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregn-4-ene-3,20-dione, (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-4b-fluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one, 11β,16α,17α,21-Tetrahydroxy-9α-fluoropregn-4-ene-3,20-dione 16,17-acetonide, 2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregn-4-ene-3,20-dione deriv., 4b-fluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one, 9-Fluoro-11beta,21-dihydroxy-16alpha,17-(isopropylidenedioxy)pregn-4-ene-3,20-dione, Corticosterone, 9-fluoro-16α,17-dihydroxy-, cyclic 16,17-acetal with Me₂CO, Pregn-4-ene-3,20-dione, 9-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α)-, Pregn-4-ene-3,20-dione, 9-fluoro-11β,16α,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone, Corticosterone, 9-fluoro-16α,17-dihydroxy-, cyclic 16,17-acetal with Me2CO

Description

Impurity Triamcinolone Acetonide EP Impurity E
Applications 9-Fluoro-16α,17-(isopropylidenedioxy) Corticosterone (Triamcinolone Acetonide EP Impurity E) is a synthetic fluorinated corticosteroid tested for inhibition of granuloma in rats and for vasoconstriction activity in human subjects; potential topical antiinflammatory agent.
References Hannah, J. et al.: J. Med. Chem., 18, 168 (1975);

• Brand: TRC

Chemical properties

• Molecular weight: 436.51
• Formula: C₂₄H₃₃FO₆
• Color/Form: Neat
• InChI: InChI=1S/C24H33FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h9,15-17,19,26,28H,5-8,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1
• InChI key: InChIKey=TZFZVQNBXVBQDC-JNQJZLCISA-N
• SMILES: CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)CC[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1