7-Fluoro-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione-d3

CAS: 78755-80-3

Ref. TR-F594552

Product Information

• Name: 7-Fluoro-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione-d3
• Synonyms: 7-Fluoro-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione, 7-Fluoro-3,4-dihydro-4-methyl-1H-benzo[e][1,4]diazepine-2,5-dione
• CAS: 78755-80-3

Description

Applications 7-Fluoro-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione-d3 is the isotope labelled analog of 7-Fluoro-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione,. 7-Fluoro-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione, is used as a reactant in the synthetic preparation of 18F-labeled radiotracers for γ-aminobutyric acid A (GABAA) receptor positron emission tomography (PET) imaging.
References Jackson, A., et al.: Bioorg. Med. Chem. Lett., 23, 821 (2013); Tedesco, R. et al.: J. Med. Chem., 49, 471 (2006);

• Brand: TRC

Chemical properties

• Molecular weight: 211.208
• Formula: C₁₀H₆D₃FN₂O₂
• Color/Form: White to Off-White Solid
• InChI: InChI=1S/C10H9FN2O2/c1-13-5-9(14)12-8-3-2-6(11)4-7(8)10(13)15/h2-4H,5H2,1H3,(H,12,14)/i1D3
• InChI key: InChIKey=BKHGZIQXTHAVNJ-FIBGUPNXSA-N
• SMILES: [2H]C([2H])([2H])N1CC(=O)Nc2ccc(F)cc2C1=O