4-(4-Fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine Hydrochloride

CAS: 1012886-75-7

Ref. TR-F595220

Product Information

• Name: 4-(4-Fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine Hydrochloride
• Synonyms: Paroxetine Hydrochloride Anhydrous Imp. G (EP), Paroxetine Imp. G (EP), Paroxetine Hydrochloride Anhydrous Imp. G (EP) as Hydrochloride, Paroxetine Related Compound E as Hydrochloride, Paroxetine Hydrochloride Hemihydrate Impurity G as Hydrochloride, Paroxetine Hydrochloride Impurity G as Hydrochloride, Paroxetine Impurity G as Hydrochloride, Paroxetine Impurity G as Hydrochloride

Description

Impurity Paroxetine EP Impurity G
Applications 4-(4-Fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine Hydrochloride (Paroxetine EP Impurity G) is the active metabolite of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) (M325910), N-Methyl-4-phenylpyridinium (MPP+), selectively destroys the dopaminergic neurons and induces the symptoms of Parkinson's disease.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gerlach, M., et al.: Eur. J. Pharmacol., 208, 273 (1991), Tipton, K., et al.: J. Neurochem., 61, 1191 (1993), Wimalasena, D., et al.: J. Biol. Chem., 279, 15298 (2004),

• Brand: TRC

Chemical properties

• Molecular weight: 227.71
• Formula: C₁₂H₁₄FN·ClH
• Color/Form: Light Yellow
• InChI: 1H, /h2-6H,7-9H2,1H3, InChI=1S/C12H14FN.ClH/c1-14-8-6-11(7-9-14)10-2-4-12(13)5-3-10
• InChI key: InChIKey=STMDKXLCBMRQPV-UHFFFAOYSA-N
• SMILES: Cl.N=C1C=C(N)C(=O)c2[nH]c(=O)ccc21