
6-Fluoro-3-[(trimethylsilyl)oxy]-2-pyrazinecarboxamide
CAS:
Ref. TR-F597083
100mg
1,022.00€

Product Information
Name:6-Fluoro-3-[(trimethylsilyl)oxy]-2-pyrazinecarboxamide
Controlled Product
Synonyms:
- 6-Fluoro-3-((trimethylsilyl)oxy)pyrazine-2-carboxamide
Brand:TRC
Description:Applications 6-Fluoro-3-[(trimethylsilyl)oxy]-2-pyrazinecarboxamide is an intermediate in synthesizing T-705RTP (T003210), a derivative of T-705 (F103350) which has activity against the lethal H5N1 influenza A viruses. T-705RTP which has the triphosphate group, gets strongly inhibited by the influenza virus RNA polymerase activity in comparison with T-705RMP (T003202).References Yousuke, F., et al.: Antimicrob Agent Chemother., 49, 981 (2005); Kiso, M., et al.: Proc. Natl. Acad. Sci. U.S.A., 107, 882 (2010);
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Chemical properties
Molecular weight:138.301
Formula:C8H12FN3O2Si
Color/Form:Neat
InChI:InChI=1S/C8H12FN3O2Si/c1-15(2,3)14-8-6(7(10)13)12-5(9)4-11-8/h4H,1-3H3,(H2,10,13)
InChI key:InChIKey=TWTWFMUQSOFTRN-JOTLNHQDSA-M
SMILES:[2H]C([2H])([2H])C([2H])([2H])[Mg]Br
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