Fluticasone Acetate

CAS: 80474-24-4

Ref. TR-F599450

Product Information

• Name: Fluticasone Acetate
• Synonyms: Androsta-1,4-diene-17-carbothioic acid, 17-(acetyloxy)-6,9-difluoro-11-hydroxy-16-methyl-3-oxo-, S-(fluoromethyl) ester, (6alpha,11beta,16alpha,17alpha)-, 6alpha,9-difluoro-17-[[(fluoromethyl)sulfanyl]carbonyl]-11beta-hydroxy-16alpha-methyl-3-oxoandrosta-1,4-dien-17alpha-yl acetate, Fluticasone Propionate Imp. C (EP), CAF (GW694301X), GW 872664X, TAF (GW675713X), 6-des-fluoro 698 (GW836850X), GSK465433A and GSK1322631A, 5-chloro-furoyl 698 (GSK180878A), TA-TAF dimer (GW871519X), unidentified impurity with RRT 1.23, disulphide dipropionate dithioketone (GR 247095X), fluticasone acetate (CCI 22341), dithio (GR 269949X), Androsta-1,4-diene-17-carbothioic acid, 17-(acetyloxy)-6,9-difluoro-11-hydroxy-16-methyl-3-oxo-, S-(fluoromethyl) ester, (6α,11β,16α,17α)-, Fluticasone acetate, Unii-1Bia3Zkx8V, [(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] acetate

Description

Impurity Fluticasone EP Impurity C
Applications Fluticasone Acetate is an impurity of Fluticasone Propionate (F599500), a derivative of Flumethasone (F455000). An antiallergic; anti-asthmatic; anti-inflammatory.
References Phillipps, G.H. et al.: J. Med. Chem., 37, 3717 (1994); Dalvi, P., et al.: Asian. J. Chem.,

• Brand: TRC

Chemical properties

• Molecular weight: 486.54
• Formula: C₂₄H₂₉F₃O₅S
• Color/Form: Neat
• InChI: InChI=1S/C24H29F3O5S/c1-12-7-15-16-9-18(26)17-8-14(29)5-6-21(17,3)23(16,27)19(30)10-22(15,4)24(12,32-13(2)28)20(31)33-11-25/h5-6,8,12,15-16,18-19,30H,7,9-11H2,1-4H3/t12-,15+,16+,18+,19+,21+,22+,23+,24+/m1/s1