Fluticasone Propionate

CAS: 80474-14-2

Ref. TR-F599500

Product Information

• Name: Fluticasone Propionate
• Synonyms: 6alpha,9-Difluoro-17-[[(fluoromethyl)sulfanyl]carbonyl]-11beta-hydroxy-16alpha-methyl-3-oxoandrosta-1,4-dien-17alpha-yl propanoate, CCI 18781, Compound A (fluticasone propionate related), unidentified impurity with RRT 1.23, disulphide dipropionate dithioketone (GR 247095X), dithio (GR 269949X), CCI 18781, Atemur Mite, Axotide, Cci 18781, Cutivate, Cutivate cream, Cyclesonide, F 9428, Flixonase, Flixonase Nasal Spray, Flixotide, Flixotide Disk, Flixotide Disks, Flixotide Inhaler, Flonase, Flonase Aq, Flovent, Flovent Diskus, Flovent Rotadisk, Flunase, Fluticasone 17-propionate, Fluticasone propionate, Fluticone, Flutide, Flutide N, Flutivate, Rotadisk, Zoflut, Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-, S-(fluoromethyl) ester, (6α,11β,16α,17α)-

Description

Applications Fluticasone Propionate is a derivative of Flumethasone, a glucocorticoid. Fluticasone Propionate has antiallergic, anti-asthmatic, and anti-inflammatory properties (1,2,3).
References (1) Meltzer, E.O., et al.: J. Allergy Clin. Immunol., 86, 221 (1990) (2) Mitchison, H.C., et al.: Gut, 32, 260 (1991) (3) Phillipps, G.H., et al.: J. Med. Chem., 37, 3717 (1994)

• Brand: TRC

Chemical properties

• Molecular weight: 500.57
• Formula: C₂₅H₃₁F₃O₅S
• Color/Form: White
• InChI: InChI=1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1
• InChI key: InChIKey=WMWTYOKRWGGJOA-JUHDKXAESA-N
• SMILES: CCC(=O)OC1(C(=O)SCF)[C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C