Fluticasone Propionate-d3

CAS: 80474-14-2

Ref. TR-F599505

Product Information

• Name: Fluticasone Propionate-d3
• Synonyms: (6a,11ß,16a,17a)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic Acid-d3 S-(Fluoromethyl) Ester, Atemur Mite-d3, CCI 18781-d3, Cutivate-d3, Flixonase-d3, Flonase-d3, Flovent-d3, Flutide-d3, Flutide N-d3, Flutivate-d3, Zofluf-d3, Atemur Mite, Axotide, Cci 18781, Cutivate, Cutivate cream, Cyclesonide, F 9428, Flixonase, Flixonase Nasal Spray, Flixotide, Flixotide Disk, Flixotide Disks, Flixotide Inhaler, Flonase, Flonase Aq, Flovent, Flovent Diskus, Flovent Rotadisk, Flunase, Fluticasone 17-propionate, Fluticasone propionate, Fluticone, Flutide, Flutide N, Flutivate, Rotadisk, Zoflut, Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-, S-(fluoromethyl) ester, (6α,11β,16α,17α)-

Description

Applications A labelled derivative of Flumethasone. An antiallergic; anti-asthmatic; anti-inflammatory.
References Meltzer, E.O., et al.: J. Allergy Clin. Immunol., 86, 221 (1990), Mitchison, H.C., et al.: Gut, 32, 260 (1991), Phillipps, G.H., et al.: J. Med. Chem., 37, 3717 (1994)

• Brand: TRC

Chemical properties

• Molecular weight: 503.59
• Formula: C₂₅H₂₈D₃F₃O₅S
• Color/Form: Neat
• InChI: InChI=1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1/i1D3
• InChI key: InChIKey=WMWTYOKRWGGJOA-GGMSSNLNSA-N
• SMILES: [2H]C([2H])([2H])CC(=O)O[C@]1(C(=O)SCF)[C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C