N-Fmoc-D-alanine

CAS: 79990-15-1

Ref. TR-F619955

Product Information

• Name: N-Fmoc-D-alanine
• Synonyms: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-alanine, (R)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]propionic Acid, (R)-N-Fmoc-alanine, 270: PN: US20070042401 PAGE: 36 Claimed Protein, 962: PN: WO2006135786 PAGE: 69 Claimed Protein, D-Fmoc-Alanine, N-(9-Fluorenylmethoxycarbonyl)-D-alanine, (2R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)propanoic acid, (2R)-2-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)propanoic acid, (2R)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]propanoic acid, (R)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]propionic acid, 270: PN: US20070042401 PAGE: 36 claimed protein, 962: PN: WO2006135786 PAGE: 69 claimed protein, <span class="text-smallcaps">D</span>-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, <span class="text-smallcaps">D</span>-Fmoc-Alanine, FMOC-<span class="text-smallcaps">D</span>-Alanine, Fmoc-D-Ala-OH, Fmoc-D-Ala-OH*H2O, N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">D</span>-alanine, N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">D</span>-alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-alanine, NALPHA-9-Fluorenylmethoxycarbonyl-D-alanine

Description

Applications N-Fmoc-D-alanine is the N-Fmoc-protected form of D-Alanine (A480995). D-Alanine is an amino acid that is commonly found in bacteria, such as Streptococcus faecalis. It is essential for the biosynthesis of peptidoglycan crosslinking sub-units that are used for bacterial cell walls. D-Alanine is also known to cause cytotoxic oxidative stress in brain tumour cells.
References Ellsworth, B., et al.: Chem. Biol., 3, 37 (1996); Ferrari, E. et al.: Nat. Biotech., 3, 1003 (1985); Stegman, L., et al.: Human Gene Ther., 9, 185 (1998); Wood, W. & Gunsalus, I.: J. Biol. Chem., 190, 403 (1951)

• Brand: TRC

Chemical properties

• Molecular weight: 311.33
• Formula: C₁₈H₁₇NO₄
• Color/Form: Neat
• InChI: InChI=1S/C18H17NO4/c1-11(17(20)21)19-18(22)23-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16H,10H2,1H3,(H,19,22)(H,20,21)/t11-/m1/s1
• InChI key: InChIKey=RAKGNVNONBJBSW-UHFFFAOYSA-N
• SMILES: COc1ccc(NC(=O)N2CCc3c2ccc2ccccc32)cc1N1CCN(C)CC1.Cl