Fmoc-Aph(Hor)-OH (~10% THF) (Degarelix intermediate)
CAS: 1253282-31-3
Ref. TR-F647563
| 1g | 381.00 € | ||
| 100mg | 83.00 € | ||
| 500mg | 261.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025
Product Information
Name:
Fmoc-Aph(Hor)-OH (~10% THF) (Degarelix intermediate)
Controlled Product
Synonyms:
- N-[(9H-fluoren-9-ylmethoxy)carbonyl]-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyrimidinyl]carbonyl]amino]-L-Phenylalanine
- Fmoc-Aph(Hor)-OH
Description:
Applications Fmoc-Aph(Hor)-OH (CAS# 1253282-31-3) is an intermediate of degarelix, a pharmeceutical hormone used in the treatment of prostate cancer. Fmoc-Aph(Hor)-OH has been used as a building block in peptide elongation reactions.
References Guryanov, I.; et al.: WO 2017103275 (2017); Takahashi, D.; et al.: Angew. Chem. Int. Ed., 56, 7803 (2017).
Notice:
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Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
542.54
Formula:
C29H26N4O7
Color/Form:
Neat
InChI:
InChI=1S/C29H26N4O7/c34-25-14-23(31-28(38)33-25)26(35)30-17-11-9-16(10-12-17)13-24(27(36)37)32-29(39)40-15-22-20-7-3-1-5-18(20)19-6-2-4-8-21(19)22/h1-12,22-24H,13-15H2,(H,30,35)(H,32,39)(H,36,37)(H2,31,33,34,38)/t23-,24-/m0/s1
InChI key:
InChIKey=TYZSMQUWFLKJFB-ZEQRLZLVSA-N
SMILES:
O=C1C[C@@H](C(=O)Nc2ccc(C[C@H](NC(=O)OCC3c4ccccc4-c4ccccc43)C(=O)O)cc2)NC(=O)N1
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Technical inquiry about: TR-F647563 Fmoc-Aph(Hor)-OH (~10% THF) (Degarelix intermediate)
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