Fmoc-valine

CAS: 68858-20-8

Ref. TR-F680000

Product Information

• Name: Fmoc-valine
• Synonyms: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valine,(2S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]-3-methylbutanoic Acid, (9-Fluorenylmethoxycarbonyl)valine, (S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoic Acid, (S)-N-Fmoc-valine, 125: PN: WO2004099237 PAGE: 36 claimed protein, 221: PN: US20070042401 PAGE: 29 claimed protein, 912: PN: WO2006135786 PAGE: 59 claimed protein, FMOC-L-valine, Fmoc-L-Val-OH, N-(9-Fluorenylmethoxycarbonyl)-L-valine, N-(9-Fluorenylmethoxycarbonyl)valine, NSC 334304, (2S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]-3-methylbutanoic acid, (S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoic acid, <span class="text-smallcaps">L</span>-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, FMOC-<span class="text-smallcaps">L</span>-valine, N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-valine, N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-valine, N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valin, N-[(9H-fluoren-9-ilmetoxi)carbonil]-L-valina, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valine, N-[(9H-fluorene-9-ylmethoxy)carbonyl]-L-valine, Nsc 334304, L-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

Description

Applications Fmoc-valine is a sterically hindered, Fmoc protected amino acid and is a derivative of L-Valine (V094205). Fmoc-valine (in addition to the other amino acids) is commonly used to synthesize 4-thiazolidinones (e.g. (E)-5-(4-Ethylbenzylidene)-2-thioxothiazolidin-4-one [E925745]) and 4-metathiazanones as well.
References Bernatowicz, M., et al.: Tetrahed. Lett., 30, 4645 (1989); Holmes, C., et al.: J. Org. Chem., 60, 7328 (1995)

• Brand: TRC

Chemical properties

• Molecular weight: 339.39
• Formula: C₂₀H₂₁NO₄
• Color/Form: Neat
• InChI: InChI=1S/C20H21NO4/c1-12(2)18(19(22)23)21-20(24)25-11-17-15-9-5-3-7-13(15)14-8-4-6-10-16(14)17/h3-10,12,17-18H,11H2,1-2H3,(H,21,24)(H,22,23)/t18-/m0/s1
• InChI key: InChIKey=UGNIYGNGCNXHTR-SFHVURJKSA-N
• SMILES: CC(C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O